Table 2 Statistics corresponding to Fig. 2. Percentage of samples in proestrus, estrus, metestrus, and diestrus as well as cycle length were analyzed using ordinary one-way ANOVA with post hoc Tukey’s multiple comparisons. Serum estradiol was analyzed using ordinary two-way ANOVA with post hoc Tukey’s correction for multiple comparisons between genotypes at each phase. Significance was set at p < 0.05 for all datasets. All significant results are in bold.

2a

Proestrus

F (2, 43) = 4.248

p = 0.0207

WT vs. LKB1^fl/fl

p = 0.2386

WT vs. Na_v1.8^LKB1

p = 0.5894

LKB1^fl/flvs. Na_v1.8^LKB1

p = 0.0162

2b

Estrus

F (2, 43) = 4.731

p = 0.0139

WT vs. LKB1^fl/fl

p = 0.0312

WT vs. Na_v1.8^LKB1

p = 0.0187

LKB1^fl/fl vs. Na_v1.8^LKB1

p = 0.9718

2c

Metestrus

F (2, 43) = 1.035

p = 0.3638

n/a

2d

Diestrus

F (2, 43) = 2.999

p = 0.0603

n/a

2e

Cycle length

F (2, 43) = 0.4728

p = 0.6265

n/a

2f

Serum estradiol

Phase: F (3, 85) = 7.018

p = 0.0003

Proestrus: WT vs. LKB1^fl/fl

p = 0.7040

Genotype: F (2, 85) = 2.049

p = 0.13.51

Proestrus: WT vs. Na_v1.8^LKB1

p = 0.5185

Phase x Genotype: F (6, 85) = 3.170

p = 0.0074

Proestrus: LKB1^fl/fl vs. Na_v1.8^LKB1

p = 0.9776

Estrus: WT vs. LKB1^fl/fl

p = 0.2748

Estrus: WT vs. Na_v1.8^LKB1

p = 0.0549

Estrus: LKB1^fl/fl vs. Na_v1.8^LKB1

p = 0.7511

Metestrus: WT vs. LKB1^fl/fl

p = 0.0765

Metestrus: WT vs. Na_v1.8^LKB1

p = 0.9317

Metestrus: LKB1^fl/fl vs. Na_v1.8^LKB1

p = 0.1492

Diestrus: WT vs. LKB1^fl/fl

p = 0.0362

Diestrus: WT vs. Na_v1.8^LKB1

p = 0.9722

Diestrus: LKB1^fl/flvs. Na_v1.8^LKB1

p = 0.0193