Fig. 2 | Scientific Reports

Fig. 2

From: Designing a linear accelerator-based “X irradiation system” for platelet products: an efficient, safe, accessible and cost-effective alternative for conventional X- or gamma irradiators

Fig. 2The alternative text for this image may have been generated using AI.

Microscopic images of colony expansion of radiation-exposed cells after PHA treatment. Microscopic images of T cell colonies following 12- and 24-hour culture of platelet product-derived MNCs in the presence of PHA 1% (a mitogen that specifically induces T cell expansion) were captured. Image (A) displays T cell colonies after 12-hour culture, whereas image (B) shows the colonies after 24-hours. Graphs (C) and (D) illustrate the significantly (P < 0.001) inhibitory effects of both gamma- and X-irradiations on T cell expansion and colony formation during both 12-hour and 24-hour culture, respectively. n = 5; ***, P < 0.001; ns, non-significant; MNC, mononuclear cell; PHA, phytohemagglutinin.

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