Fig. 4
From: Foxp3 + Treg-derived IL-10 promotes colorectal cancer-derived lung metastasis
Foxp3 + Tregs and myeloid cells exhibit high IL-10Ra expression. (A–D) Representative FACS plots and ΔMFI quantification of IL-10Ra expression in immune cells isolated from (A,B) healthy lungs (n ≥ 4 mice per group) or (C,D) lungs with metastasis 21 days post i.v. MC38 cancer cell injection (n ≥ 5 mice per group). (E) Representative FACS plots and (F) ΔMFI quantification of IL-10Ra expression in lung CD3- immune cells isolated from lungs with metastasis. Data are presented as mean ± SEM. Non-significant (ns): p > 0.05; *p < 0.05; ***p < 0.001; ****p < 0.0001, as calculated by one-way ANOVA (Bonferroni) with Bonferroni post hoc tests.
