Fig. 5 | Scientific Reports

Fig. 5

From: A computational model that integrates unrestricted callus growth, mechanobiology, and angiogenesis can predict bone healing in rodents

Fig. 5

Histological analysis of tissue progression and differentiation post-fracture for one representative sample at each timepoint between days (1–21). This represents histology slides at various time points post-fracture using H&E staining (A) and (B) Movat’s Pentachrome staining with higher magnification views of cartilage and new bone outlined in blue and orange, respectively. The images illustrate the tissue progression and differentiation trend within the fracture site. The images illustrate the progression and differentiation of tissue within the fracture site. Parts (C) and (D) provide detailed, zoomed-in views of specific regions on days 14 and 21, highlighting chondrocytes and osteoblasts within the fracture window, respectively.

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