Table 4 Univariate analysis of prognostic factors for overall survival and progression-free survival of diffuse large B-cell lymphoma.
From: Survival of HIV associated diffuse large B-cell lymphoma and Burkitt lymphoma in China
Overall survival | Progression free survival | |||
|---|---|---|---|---|
HR (95% CI) from Cox regression | p-value from log rank test | HR (95% CI) from Cox regression | p-value from log rank test | |
Age > 60 | 1.431 (0.594, 3.448) | 0.424 | 3.018 (0.712, 12.780) | 0.134 |
High Risk IPI | 3.188 (0.503, 20.188) | 0.218 | 0.965 (0.122, 7.641) | 0.973 |
ECOG PS > 1 | 0.973 (0.291, 3.261) | 0.965 | 1.237 (0.316, 4.847) | 0.760 |
Number of extranodal sites ≥ 2 | 2.117 (0.748, 5.994) | 0.158 | 3.521 (0.965, 12.841) | 0.057 |
Bulky disease | 1.776 (0.437, 7.223) | 0.423 | 0.949 (0.168, 5.360) | 0.952 |
B symptoms | 0.444 (0.152, 1.301) | 0.139 | 0.430 (0.123, 1.504) | 0.187 |
Bone marrow involvement | 0.797 (0.247, 2.576) | 0.705 | 1.801 (0.357, 9.079) | 0.476 |
Elevated LDH | 1.201 (0.352, 4.104) | 0.770 | 1.525 (0.300, 7.750) | 0.611 |
CNS Involvement | 2.490 (0.857, 7.231) | 0.094 | 4.589 (1.202, 17.516) | 0.026 |
CD4 count < 100/µL | 0.730 (0.241, 2.206) | 0.577 | 0.693 (0.163, 2.956) | 0.621 |
Rituximab use | 0.280 (0.060, 1.315) | 0.107 | 0.211 (0.032, 1.376) | 0.104 |
