Table 5 Participants’ characteristics, by BMI status.

From: Investigation of the impact of exposure to trace elements on health and disease from the ToxiLaus study

Characteristic

Normal,

N = 28111

Overweight,

N = 21351

Obese,

N = 9201

p-value

Age (Years)

49.6 (36.8, 70.7)

54.3 (37.3, 73.0)

57.0 (38.5, 71.9)

< 0.0012

Smoking

   

< 0.0013

     Non smoker

1,954 (70%)

1,588 (74%)

735 (80%)

 

     Smoker

857 (30%)

547 (26%)

185 (20%)

 

Sex

   

< 0.0013

     Women

1,778 (63%)

872 (41%)

441 (48%)

 

     Men

1,033 (37%)

1,263 (59%)

479 (52%)

 

Diabetes

   

< 0.0013

     No

2,746 (98%)

2,006 (94%)

724 (79%)

 

     Yes

65 (2%)

129 (6%)

196 (21%)

 

Metabolic syndrome

  

< 0.0013

     No

2,676 (95%)

1,517 (71%)

300 (33%)

 

     Yes

135 (5%)

618 (29%)

620 (67%)

 

BMI, (kg/m2)

22.5 (18.9, 24.8)

27.1 (25.2, 29.6)

32.6 (30.2, 40.4)

< 0.0012

Creatinine, (µg/L)

1.39 (0.40, 2.85)

1.45 (0.46, 2.91)

1.36 (0.50, 2.81)

0.0032

TE concentrations

    

     Li, (µg/L)

17.5a (7.21, 110)

17.3 (6.93, 98.8)

17.1a (6.38, 108)

0.0252

     Be, (ng/L)

1.1 (0.4, 4.9)

1.0 (0.4, 4.6)

1.1 (0.4, 4.5)

0.112

     Al, (µg/L)

4.15 (0.95, 20.3)

4.12a (0.94, 20.3)

4.42a (1.08, 22.1)

0.0182

     V, (µg/L)

0.12 (0.06, 0.42)

0.12 (0.06, 0.39)

0.13 (0.06, 0.38)

0.32

     Cr, (µg/L)

0.20 (0.06, 0.89)

0.19 (0.06, 0.88)

0.21 (0.06, 0.96)

0.22

     Mn, (µg/L)

0.22a (0.11, 0.99)

0.22a (0.10, 0.87)

0.23 (0.11, 0.95)

0.0092

     Fe, (µg/L)

4.56 (1.83, 21.9)

4.47a (1.74, 18.2)

5.08a (1.73, 19.1)

< 0.0012

     Co, (µg/L)

0.17a, b (0.08, 1.05)

0.15b (0.07, 0.85)

0.16a (0.08, 0.96)

< 0.0012

     Ni, (µg/L)

1.06a, b (0.39, 3.45)

0.93b (0.34, 3.23)

0.93a (0.35, 3.05)

< 0.0012

     Cu, (µg/L)

8.93a (5.73, 17.8)

8.92b (5.50, 18.9)

9.80a, b (5.81, 21.9)

< 0.0012

     Zn, (µg/L)

277a (84.9, 675)

314b (106, 758)

354c (117, 875)

< 0.0012

     As, (µg/L)

16.4a (3.91, 157)

15.0b (3.65, 146)

13.2a, b (3.23, 139)

< 0.0012

    Se, (µg/L)

20.7a (13.5, 35.5)

20.32b (13.2, 36.3)

21.2a, b (13.1, 37.7)

0.0032

    Mo, (µg/L)

30.8a (11.0, 68.0)

27.6a, b (8.62, 66.9)

29.5b (10.6, 70.3)

< 0.0012

     Ag, (µg/L)

0.03a (0.01, 0.11)

0.03a (0.01, 0.10)

0.03 (0.01, 0.11)

0.0202

     Cd, (µg/L)

0.44a (0.15, 1.49)

0.41a (0.15, 1.40)

0.43 (0.16, 1.32)

0.0122

     Sn, (µg/L)

0.57a (0.19, 2.31)

0.51a (0.17, 2.73)

0.55 (0.17, 2.77)

< 0.0012

     Sb, (µg/L)

0.04a (0.02, 0.16)

0.04 (0.02, 0.20)

0.05a (0.02, 0.18)

0.0242

     I, (µg/L)

92.7a (48.9, 206)

93.2 (49.6, 205)

95.7a (51.5, 216.5)

0.0302

     Hg, (µg/L)

1.11a (0.28, 3.83)

0.90b (0.23, 3.09)

0.83c (0.20, 2.87)

< 0.0012

     Tl, (µg/L)

0.18a, b (0.09, 0.45)

0.17b (0.09, 0.42)

0.17a (0.08, 0.41)

< 0.0012

     Pb, (µg/L)

1.30 (0.51, 4.26)

1.33 (0.49, 4.00)

1.29 (0.49, 3.86)

0.112

     Bi, (ng/L)

5a (2, 36)

5a (2, 40)

5 (2, 26)

0.0152

1 Median (5%, 95%)

2 Kruskal-Wallis rank sum test

3 Pearson’s Chi-squared test

  1. P values < 0.05 are indicated in bold, highlighting a statistical difference between groups
  2. a, b,c Post-hoc Dunn’s test. Results are shown with superscript letters indicating statistical differences between groups. If only two groups are statistically different, the same letter is assigned to both. If all three groups are statistically different from one another, letter “a”, “b” and “c” will be assigned. Detailed Dunn’s test results are shown in Supplementary Table S5.