Table 6 The binding energy of the interacted etoxazole with DNA molecules.
From: Alleviatory efficacy of achillea millefolium L. in etoxazole-mediated toxicity in allium cepa L
DNA Molecule | DNA Sequence | Free energy of binding (kcal/mol) | Inhibition constant (Ki) | Interacting nucleic acids (Chain: nucleotide) |
|---|---|---|---|---|
B-DNA Dodecamer (1BNA) | 5’-CGCGAATTCGCG-3’ | −7.73 | 2.14 µM | A: T8 A: C9 A: G10 A: C11 B: G16 B: A17 B: A18 |
B-DNA Dodecamer D (195D) | 5’-CGCGTTAACGCG-3’ | −7.88 | 1.68 µM | A: A7 A: A8 B: T17 B: T18 B: A19 |
DNA (1CP8) | 5’-TTGGCCAA-3’ | −6.27 | 25.41 µM | A: G4 B: C6 B: A7 |
