Fig. 3 | Scientific Reports

Fig. 3

From: Therapy response monitoring in blood plasma from esophageal adenocarcinoma patients using cell-free DNA methylation profiling

Fig. 3

Dynamic change in estimated tumor fraction in longitudinally collected blood plasma samples from 33 EAC patients. (A) Heatmap showing estimated tumor fractions per patient and sampled timepoint. The x-axis indicates the time in months relative to the time of surgery (timepoint t1). Grey boxes indicate tumor fractions below the cut-off of 2.6%, blue between 2.6% and 15% and dark blue more than 15%. (B–D) Timelines showing increasing tumor fractions of three patients that eventually presented with a tumor fraction that is higher than 15% (after surgery).

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