Fig. 7

The role of ESM1/Akt/mTOR and ESM1/Ras axis in KIRC progression. The effect of ESM1/Akt/mTOR and ESM1/Ras axis on KIRC cell proliferation, invasion and angiogenesis by MTT (A), Transwell invasion assay (B) (The number of biological replicates is n = 3, The magnification was × 100), and Tube formation assay (C) (The number of biological replicates is n = 3, The magnification was × 100), respectively.