Table 4 Diagnostic efficacy of different cutoff values for BALF-GM in IPA patients.

From: Metagenomic next-generation sequencing and galactomannan testing for the diagnosis of invasive pulmonary aspergillosis

Cutoff value

AUC (95%CI)

Sensitivity%

Specificity%

PPV%

NPV %

Youden Index

0.5

0.80 (0.74–0.85)

67.50

79.49

77.14

70.45

0.47

0.8

0.80 (0.74–0.85)

53.33

88.89

83.12

65.00

0.42

1.0

0.80 (0.74–0.85)

48.33

94.02

89.23

63.95

0.42

  1. IPA, invasive pulmonary aspergillosis; GM, galactomannan antigen; BALF, bronchoalveolar lavage fluid; PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve.
Back to article page