Table 3 Burden (DALYs) of testicular cancer in adolescents and young adults and their temporal trends from 1990 to 2021, using Joinpoint analysis.
Characteristics | Number of cases, 1990 (95% UI) | Age-standardized rate per 100,000 population, 1990 (95% CI) | Number of cases, 2021 (95% UI) | Age-standardized rate per 100,000 population, 2021 (95% CI) | AAPC (Age-standardized rate, 95% CI) | p |
|---|---|---|---|---|---|---|
Global | 282,637 (262,651–304,571) | 26.02 (24.2–28.04) | 376,564 (348,929–408,401) | 24.82 (22.99–26.91) | −0.16 (−0.32 to 0) | 0.0555 |
High SDI | 70,161 (66,141–74,550) | 38.68 (36.46–41.11) | 46,537 (42,067–52,050) | 24.34 (22–27.22) | −1.41 (−1.65 to −1.16) | < 0.001 |
High-middle SDI | 71,625 (65,522–79,233) | 31.05 (28.41–34.34) | 62,951 (56,073–70,763) | 26.37 (23.42–29.73) | −0.57 (−0.91 to −0.23) | 0.001 |
Middle SDI | 74,607 (68,671–81,166) | 20.06 (18.47–21.82) | 126,951 (115,969–138,193) | 26.74 (24.43–29.08) | 0.91 (0.63 to 1.2) | < 0.001 |
Low-middle SDI | 49,017 (38,477–61,173) | 22.67 (17.8–28.28) | 97,261 (81,150–117,548) | 24.48 (20.43–29.58) | 0.25 (0.15 to 0.36) | < 0.001 |
Low SDI | 16,817 (11,466–22,529) | 19.86 (13.6–26.54) | 42,541 (33,515–52,719) | 20.53 (16.18–25.42) | 0.10 (−0.01 to 0.20) | 0.0650 |
High-income Asia Pacific | 7064 (6430–7821) | 20.82 (18.95–23.05) | 3084 (2643–3652) | 11.32 (9.70–13.40) | −1.93 (−3.29 to −0.56) | 0.0060 |
High-income North America | 20,420 (19,108–21,994) | 34.45 (32.23–37.11) | 20,314 (18,346–22,722) | 31.96 (28.86–35.75) | −0.12 (−0.33 to 0.10) | 0.2767 |
Western Europe | 37,724 (34,853–41,177) | 50.39 (46.55–55.01) | 17,033 (14,532–20,274) | 24.82 (21.17–29.56) | −2.22 (−2.44 to −20) | < 0.001 |
Australasia | 2006 (1639–2422) | 48.67 (39.74–58.81) | 1493 (1095–2035) | 27.04 (19.77–36.95) | −2.07 (−2.49 to −1.65) | < 0.001 |
Eastern Europe | 17,849 (15,857–20,052) | 40.2 (35.76–45.14) | 13,685 (11,863–15,809) | 37.13 (32.18–42.91) | −0.27 (−0.88 to 0.34) | 0.3810 |
Central Europe | 20,627 (19,065–22,499) | 86.34 (79.75–94.20) | 12,480 (11,108–13,959) | 66.26 (58.89–74.24) | −0.77 (−1.42 to −0.12) | 0.0208 |
Southern Latin America | 9774 (7670–12,344) | 104.67 (82.24–132.06) | 14,552 (11,690–17,701) | 110.66 (88.83–134.71) | 0.26 (−0.71 to 1.24) | 0.5959 |
East Asia | 34,578 (28,032–42,342) | 12.07 (9.80–14.78) | 21,345 (16,642–26,521) | 8.11 (6.29–10.11) | −1.23 (−1.81 to −0.65) | < 0.001 |
Central Asia | 3244 (2677–3972) | 23.15 (19.14–28.22) | 4779 (4011–5737) | 24.35 (20.43–29.26) | 0.12 (−0.42 to 0.67) | 0.6572 |
North Africa and Middle East | 9926 (6404–15,233) | 15.16 (9.81–23.23) | 18,849 (14,575–24,466) | 14.16 (10.94–18.42) | −0.26 (−0.52 to 0.00) | 0.0532 |
Andean Latin America | 3086 (2003–4667) | 41.83 (27.22–63.17) | 6896 (4843–9455) | 50.12 (35.17–68.75) | 0.51 (−0.09 to 1.11) | 0.0956 |
Southeast Asia | 13,169 (10,908–16,008) | 13.99 (11.60–17.00) | 23,078 (18,155–29,945) | 16.24 (12.79–21.07) | 0.48 (0.38 to 0.59) | < 0.001 |
Tropical Latin America | 9092 (8188–10,113) | 29.24 (26.35–32.51) | 21,770 (19,291–24,440) | 49.04 (43.42–55.09) | 1.71 (1.38 to 2.03) | < 0.001 |
Southern Sub-Saharan Africa | 1656 (1271–2067) | 16.75 (12.89–20.85) | 3221 (2563–4037) | 18.85 (14.99–23.63) | 0.31 (0.06 to 0.56) | 0.0162 |
Caribbean | 357 (292–435) | 4.98 (4.09–6.07) | 1335 (1058–1684) | 14.59 (11.57–18.42) | 3.61 (1.67 to 5.58) | < 0.001 |
Central Latin America | 18,189 (17131–19,327) | 55.42 (52.2–58.89) | 50,424 (45,475–55,480) | 101.23 (91.27–111.41) | 1.94 (1.34 to 2.55) | < 0.001 |
South Asia | 62,927 (49,896–77,774) | 29.62 (23.54–36.57) | 107,816 (88,503–131,204) | 27.02 (22.19–32.88) | −0.30 (−0.44 to −0.15) | < 0.001 |
Central Sub-Saharan Africa | 1439 (854–2250) | 14.70 (8.75–22.9) | 4500 (2583–7398) | 17.60 (10.1–28.87) | 0.58 (0.44 to 0.73) | < 0.001 |
Oceania | 123 (74–186) | 9.16 (5.61–13.80) | 229 (152–334) | 8.01 (5.31–11.67) | −0.37 (−0.69 to −0.04) | 0.0282 |
Western Sub-Saharan Africa | 3015 (2327–3805) | 9.17 (7.10–11.57) | 7110 (5359–9217) | 8.42 (6.35–10.92) | −0.25 (−0.47 to −0.03) | 0.0258 |
Eastern Sub-Saharan Africa | 6374 (4230–8737) | 20.18 (13.47–27.53) | 22,571 (16,687–29,404) | 28.47 (21.15–37) | 1.10 (1.03 to 1.18) | < 0.001 |
