Table 3 Quality of life parameters according to the surgical techniques APR (abdominoperineal resection) and LAR (low anterior resection.

Category	Time-point	APR			LAR*			p value
Category	Time-point	N	Mean	SD	N	Mean	SD	[conf interval]
QL2	Baseline	229	62.19	20.27	720	63.25	21.9318	0.499 [-4.1, 2]
	After treatment	152	57.29	22.31	456	61.51	21.0659	0.042 [-8.3, 0.2]
	FU12 months	130	64.42	20.75	403	65.12	20.4591	0.74 [-4.8, 3.4]
	FU36 months	85	65.19	20.86	300	67.50	20.9459	0.371 [-7.4, 2.8]
RF2	Baseline	236	81.36	24.95	738	83.04	25.7466	0.371 [-5.4, 2.0]
	After treatment	154	52.71	29.98	463	58.64	30.7591	0.035 [-11.5, -0.4]
	FU12 months	133	61.15	28.11	408	66.59	29.2782	0.057 [-11, 0.2]
	FU36 months	89	63.11	30.30	308	71.65	28.0975	0.019 [-15.6, -1.4]
SF	Baseline	232	79.17	24.85	724	76.84	27.0336	0.226 [-1.4, 6.1]
	After treatment	154	63.00	30.86	457	63.79	30.7808	0.781 [-6.5, 4.9]
	FU12 months	130	70.77	27.30	404	67.16	30.1367	0.203 [-2, 9.2]
	FU36 months	86	67.05	27.17	301	70.93	29.4597	0.254 [-10.6, 2.8]
PF2	Baseline	237	88.14	15.04	741	89.57	15.718	0.208 [-3.7, 0.8]
	After treatment	157	70.41	22.71	467	76.90	20.4611	0.002 [-10.5, -2.5]
	FU12 months	132	75.74	20.84	408	81.43	19.1133	0.006 [-9.7, -1.6]
	FU36 months	89	74.57	21.66	308	83.20	19.0545	0.001 [-13.7, -3.6]
CT-side	Baseline	234	7.45	11.95	734	8.71	13.8294	0.179 [-3.1, 0.6]
effects	After treatment	154	25.97	22.73	464	30.30	25.2643	0.047 [-8.6, 0]
	FU12 months	128	10.76	14.22	406	15.54	18.2521	0.002 [-7.8, -1.7]
	FU36 months	87	12.90	14.56	302	11.87	16.8819	0.575 [-2.6, 4.7]

* Including intersphincteric resection (ISR); with respect to QL2 (global health status), RF2 (role functioning), SF (social functioning), PF2.

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