Table 2 Univariate and multivariate logistic regression fitting results on associated factors of live birth.
Variables | Live birth (Yes) | |||
|---|---|---|---|---|
Univariate model OR (90% CI) | p value | Multivariate model OR (95% CI) | p value | |
Age of husband (Ref: < = 35 years old) | ||||
36–39 years old | 0.78 (0.71–0.85) | < 0.01 | 1.03 (0.91–1.17) | 0.62 |
> = 40 years old | 0.49 (0.44–0.54) | < 0.01 | 0.95 (0.82–1.10) | 0.46 |
Ethnicity of husband (Ref: Han majority) | ||||
Minority | 1.09 (1.01–1.18) | < 0.10 | 1.04 (0.95–1.15) | 0.39 |
Maternal age (Ref: < = 35 years old) | ||||
36–39 years old | 0.64 (0.59–0.70) | < 0.01 | 0.68 (0.60–0.77) | < 0.01 |
> = 40 years old | 0.16 (0.13–0.19) | < 0.01 | 0.20 (0.15–0.25) | < 0.01 |
Maternal ethnicity (Ref: Han majority) | ||||
Minority | 1.07 (0.99–1.15) | 0.14 | ||
Maternal BMI (Ref: Normal) | ||||
Underweight | 1.02 (0.89–1.16) | 0.84 | 0.96 (0.81–1.13) | 0.60 |
Overweight and obesity | 0.91 (0.84–0.98) | < 0.05 | 0.89 (0.80–0.98) | < 0.05 |
Duration of infertility (+ 1 year) | 0.95 (0.94–0.96) | < 0.01 | 0.96 (0.95–0.98) | < 0.01 |
Type of infertility (Ref: Primary) | ||||
Secondary | 0.95 (0.88–1.02) | 0.22 | ||
Cause of infertility (Ref: Female factor) | ||||
Male factor | 1.19 (1.06–1.34) | < 0.05 | 0.99 (0.83–1.17) | 0.87 |
Mixed factor | 1.04 (0.96–1.13) | 0.41 | 0.96 (0.84–1.09) | 0.53 |
Unexplained | 1.11 (0.98–1.26) | 0.16 | 1.06 (0.90–1.23) | 0.50 |
Previous ART Cycles (+ 1) | 0.62 (0.58–0.65) | < 0.01 | 0.70 (0.65–0.76) | < 0.01 |
Insemination method (Ref: IVF) | ||||
ICSI | 0.94 (0.86–1.03) | 0.29 | ||
Starting dosage of Gn (Ref: Very low level) | ||||
Low level | 0.85 (0.77–0.94) | < 0.01 | 0.95 (0.83–1.09) | 0.44 |
Moderate level | 0.84 (0.71–0.98) | < 0.10 | 0.91 (0.72–1.15) | 0.44 |
High level | 0.68 (0.62–0.75) | < 0.01 | 0.93 (0.76–1.15) | 0.51 |
Duration of Gn (Ref: Very low level) | ||||
Low level | 1.57 (1.39–1.77) | < 0.01 | 1.26 (1.08–1.48) | < 0.01 |
Moderate level | 1.74 (1.58–1.93) | < 0.01 | 1.21 (1.04–1.42) | < 0.05 |
High level | 1.94 (1.74–2.16) | < 0.01 | 1.22 (1.00–1.50) | 0.06 |
Total dosage of Gn (Ref: Very low level) | ||||
Low level | 1.36 (1.23–1.50) | < 0.01 | 1.27 (1.09–1.47) | < 0.01 |
Moderate level | 1.17 (1.06–1.30) | < 0.01 | 1.30 (1.07–1.56) | < 0.01 |
High level | 1.09 (0.99–1.21) | 0.14 | 1.21 (0.96–1.53) | 0.11 |
Basal FSH (Ref: Very low level) | ||||
Low level | 1.01 (0.92–1.12) | 0.82 | 0.98 (0.87–1.12) | 0.81 |
Moderate level | 1.17 (1.06–1.29) | < 0.01 | 1.12 (0.99–1.27) | 0.08 |
High level | 1.16 (1.05–1.28) | < 0.05 | 1.16 (1.02–1.33) | < 0.05 |
Basal E2 (Ref: Very low level) | ||||
Low level | 0.96 (0.87–1.06) | 0.52 | ||
Moderate level | 0.97 (0.88–1.07) | 0.66 | ||
High level | 0.95 (0.86–1.05) | 0.37 | ||
Basal LH (Ref: Very low level) | ||||
Low level | 1.08 (0.98–1.19) | 0.21 | 1.00 (0.88–1.14) | 0.95 |
Moderate level | 1.21 (1.09–1.33) | < 0.01 | 1.09 (0.96–1.24) | 0.18 |
High level | 1.19 (1.08–1.32) | < 0.01 | 1.00 (0.87–1.14) | 0.96 |
Progressive sperm motility (Ref: Very low level) | ||||
Low level | 0.91 (0.82–1.00) | < 0.01 | 0.88 (0.77–1.01) | 0.07 |
Moderate level | 0.87 (0.79–0.96) | < 0.05 | 0.80 (0.69–0.94) | < 0.01 |
High level | 0.86 (0.78–0.94) | < 0.01 | 0.77 (0.65–0.90) | < 0.01 |
Non-progressive sperm motility (Ref: Very low level) | ||||
Low level | 1.16 (1.05–1.28) | < 0.05 | 1.02 (0.90–1.15) | 0.81 |
Moderate level | 1.09 (0.99–1.21) | 0.14 | 0.97 (0.86–1.11) | 0.69 |
High level | 1.12 (1.01–1.23) | < 0.01 | 1.05 (0.92–1.19) | 0.49 |
E2 on HCG day (Ref: Very low level) | ||||
Low level | 1.88 (1.70–2.07) | < 0.01 | 1.47 (1.29–1.67) | < 0.01 |
Moderate level | 1.65 (1.50–1.82) | < 0.01 | 1.20 (1.04–1.37) | < 0.05 |
High level | 0.90 (0.81–1.00) | < 0.10 | 0.66 (0.57–0.77) | < 0.01 |
LH on HCG day (Ref: Very low level) | ||||
Low level | 1.05 (0.95–1.16) | 0.41 | 1.10 (0.98–1.25) | 0.12 |
Moderate level | 1.13 (1.03–1.25) | < 0.05 | 1.29 (1.14–1.47) | < 0.01 |
High level | 0.68 (0.62–0.76) | < 0.01 | 1.07 (0.93–1.24) | 0.34 |
P on HCG day (Ref: Very low level) | ||||
Low level | 1.09 (0.99–1.20) | 0.14 | 0.96 (0.85–1.08) | 0.49 |
Moderate level | 0.98 (0.89–1.08) | 0.78 | 0.89 (0.78–1.01) | 0.07 |
High level | 0.46 (0.41–0.51) | < 0.01 | 0.46 (0.40–0.54) | < 0.01 |
