Fig. 4 | Scientific Reports

Fig. 4

From: Fluorofenidone alleviates cigarette smoke exposure-induced chronic lung injury by targeting ferroptosis

Fig. 4

AKF suppressed the inflammatory response and ferroptosis in BEAS-2B cells treated with CSE. (A) The cell viability was determined using CCK8 assay. (B–D) The contents of IL-1β, IL-6 and TNF-α in cell supernatant. (E–F) The level of MDA and GSH in cell supernatant. (G) Western blotting of ACSL4 and GPX4 in cells. (H) Morphological characteristics of ferroptosis was observed by transmission electron microscopy. # means compared to the CS/LPS group, P < 0.05.

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