Fig. 5
From: SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation
IL10RB and hypertension served as mediators for the causal effect of SGLT-2 inhibitors on ICH. β0, the relationship between SGLT-2 inhibitors and Intracerebral haemorrhage; β1, the relationship between SGLT-2 inhibitors and the inflammatory biomarker (hypertension), β2, the inflammatory biomarker (hypertension) to ICH, were estimated using the inverse-variance weighted approach in Mendelian randomization.
