Fig. 2
The effects of body mass index (id: ieu-a-835) on 249 metabolic traits and 249 metabolic traits on nonalcoholic fatty liver disease (id: ebi-a-GCST90091033). We visualized the effects of body mass index (id: ieu-a-835) on 249 metabolic traits and 249 metabolic traits on nonalcoholic fatty liver disease (id: ebi-a-GCST90091033). The outermost boundary of this circular heatmap consists of the names of 249 metabolites and their corresponding IDs. As shown in the legend, the outer two rings represent the beta values from the IVW method for BMI on each metabolite, and the beta values from the IVW method for each metabolite on NAFLD (from outer to inner). The innermost two rings represent the p-values from the IVW method for BMI on each metabolite, and the p-values from the IVW method for each metabolite on NAFLD (from outer to inner). All analyses were performed using a two-step Mendelian randomization approach. IVW: Inverse Variance Weighted method; q_value: The P value post FDR method (Benjamini and Hochberg) corrected; BMI: body mass index; NAFLD: nonalcoholic fatty liver disease.
