Table 1 Maternal demographics, obstetric and laboratory data of two groups.
Variable | Maternal euthyroid group (ETG, n = 35) | Maternal subclinical hypothyroid group (SHG, n = 35) | P |
|---|---|---|---|
Age (years) Mean ± SD | 30.8 ± 5.0 | 30.1 ± 6.1 | 0.609a |
Duration of T1DM (years) Mean ± SD | 14.8 ± 9.5 | 14.1 ± 8.0 | 0.798a |
Years of onset T1DM (years) Mean ± SD | 16.3 ± 9.8 | 16.1 ± 8.8) | 0.908a |
Height (cm) Mean ± SD | 166.6 ± 5.7 | 165.2 ± 4.9 | 0.610a |
BMI before pregnancy (kg/m2) Mean ± SD | 24.7 ± 5.3 | 23.0 ± 4.3 | 0.158a |
BMI at the time of CS (kg/m2) Mean ± SD | 29.2 ± 5.0 | 27.6 ± 4.5 | 0.160a |
Primiparous n (%) | 21 (60.0) | 20 (57.1) | |
Multiparous n (%) | 14 (40.0) | 15 (42.9) | > 0.9b |
HbA1c in the first trimester (%) Mean ± SD | 6.5 ± 1.4 | 6.2 ± 0.8 | 0.349a |
HbA1c in the second trimester (%) Mean ± SD | 6.5 ± 1.4 | 6.2 ± 0.8 | 0.349a |
HbA1c in the third trimester (%) Mean ± SD | 6.1 ± 1.1 | 6.1 ± 0.7 | 0.958a |
TSH in the first trimester (mIU/L); Median IQR | 1.7 (1.1–2.0) | 3.2 (2.8–4.2) | < 0.001c |
fT3 in the first trimester (pmol/L); Median IQR | 3.9 (3.6–4.3) | 3.6 (3.4–4.1) | 0.132c |
fT4 in the first trimester (pmol/L); Median IQR | 11.6 (11.0–12.2) | 11.7 (11.0–12.8) | 0.327c |
BDNF in the first trimester (ng/L); Median IQR | 861.8 (571.9–1031.0) | 586.1 (459.1–819.5) | 0.831c |
BDNF at the time of CS (ng/L); Median IQR | 613.8 (403.5–1031.0) | 586.1 (459.1–819.5) | 0.831c |
Maternal serum glucose at the time of CS (mmol/L) Medina IQR | 5.4 (4.3.7.0) | 5.2 (3.9–6.0) | 0.184c |
Maternal telomere length (T/S) Mean ± SD | 2.1 ± 1.3 | 1.4 ± 0.9 | 0.015a |