Table 2 Neonatal and laboratory data of two study groups.

From: Influence of subclinical hypothyroidism and brain-derived neurotropic factor on telomere length dynamics in type 1 diabetic pregnancies and their newborns

Variable

Maternal euthyroid group (ETG, n = 35) Median IQR;

Maternal subclinical hypothyroid group (SHG, n = 35)

P

Male n (%)

15 (42.9%

16 (45.7%)

 

Female n (%)

20 (57.1%)

19 (54.3%)

0.500b

Term birth n (%)

31 (88.6%)

32 (91.4%)

0.500b

Birthweight (g) Mean ± SD

3456.6 ± 624.7

3763.1 ± 601.2

0.040a

LGA n (%)

6 (17.2%)

14 (40%)

 

AGA

29 (82.8%)

21 (60%)

0.034b

Apgar index at 1 min Mean ± SD

9.8 ± 0.5

9.9 ± 0.4

0.597a

Apgar index at 5 min Mean ± SD

9.8 ± 0.8

9.9 ± 0.2

0.418a

Umbilical vein serumTSH (mIU/L) Median IQR

4.6 (3.7–6.2)

5.3 (4.1–8.1)

0.162c

Umbilical vein serum fT3 (pmol/L) Median IQR

2.5 (2.1–2.8)

2.6 (2.4–3.0)

0.105c

Umbilical vein serum fT4 (pmol/L) Median IQR

12.7 (12.1–13.3)

13.0 (12.3–14.3)

0.082c

Umbilical vein serum C-peptide (pmol/L) Median IQR

0.75 (0.56–1.95)

0.84 (0.51–1.55)

0.767c

Umbilical vein glucose (mmol/L) Median IQR

4.4 (2.1–6.2)

4.5 (3.2–5.3)

0.492c

IR HOMA-2 Median IQR

1.6 (1.2–3.0)

1.8 (1.1–3.1)

0.846c

Leptin (ng/L) Median IQR

13.1 (8.1–23.8)

13.9 (8.9–28.3)

0.752c

Umbilical vein serum BDNF (ng/L) Median IQR

299.8 (185.7–450.4)

303.8 (253.6–433.0)

0.505c

Neonatal telomere length (T/S) Mean ± SD

2.7 ± 1.4

2.0 ± 0.9

0.010a

  1. Data are n (%); median IQR; and mean (SD).
  2. BMI body mass index, BDNF brain-derived neurotropic factor, TSH thyroid-stimulating hormone, fT3 triiodthyronine, fT4 thyroxine, IR HOMA-2 insulin resistance HOMA-2.
  3. at-test. χ2 test; cMann–Whitney test.