Fig. 6 | Scientific Reports

Fig. 6

From: Impact of obesity on iron metabolism and the effect of intravenous iron supplementation in obese patients with absolute iron deficiency

Fig. 6

Changes in iron related levels before and after intravenous iron sucrose infusion by body mass index category. Bars show the median and interquartile range of serum ferritin (A), Hb (B), sTfR (C), transferrin (E), TfSI (F) and sideremia (G) before (baseline time-point, B) and after (final time-point, F) intravenous iron sucrose infusion and the respective fold change per BMI category. Body mass index categories: healthy weight (18.5–24.9 kg/m2), pre-obese (25.0–29.9 kg/m2), obese (≥ 30–34.9 kg/m2). HW, healthy weight; B, baseline time-point; F, final time-point; Hb, hemoglobin; sTfR, soluble transferrin receptor and TfSI, transferrin saturation index. Differences between paired time-points were determined using Wilcoxon signed rant test and differences between BMI categories were determined using Mann–Whitney U-test. Only comparisons with p-value < 0.1 are indicated. Ө 0.1 > p-value ≥ 0.05; *0.01 ≤ p-value < 0.05; **0.001 ≤ p-value < 0.01; ***0.0001 ≤ p-value < 0.001; **** p-value < 0.0001.

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