Fig. 3

Effect of LRG1 on IRI-induced kidney inflammation. (a–d) Relative renal mRNA expression of IL-6, TNFα, F4/80 and CCL2 (n = 6). Values are presented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 when compared between indicated groups by 2-way ANOVA with Bonferroni’s post hoc test. WT wildtype, KO knockout, I/R ischemia–reperfusion, IL-6 interleukin-6, TNFα tumor necrosis factor α, CCL2 chemotactic-C–C-motif-chemokine-ligand-2; ●, WT; ○, KO.