Fig. 5 | Scientific Reports

Fig. 5

From: Leucine-rich alpha-2-glycoprotein 1 deficiency suppresses ischemia–reperfusion injury-induced renal fibrosis

Fig. 5

Effect of LRG1 on renal TGF-β and pro-fibrotic genes expression after IRI. (a,b) Relative renal mRNA expression of TGF-β and FN (n = 6). (c,d) Representative western blots and quantitative analysis of αSMA in the kidney on postoperative day 28 (n = 6). Values are expressed as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 when compared between indicated groups by 2-way ANOVA with Bonferroni’s post hoc test. WT wild-type, KO LRG1 knock out, I/R ischemia–reperfusion, TGF transforming growth factor, FN fibronectin, αSMA α-smooth muscle actin; ●, WT; ○, KO.

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