Fig. 9

Potential mechanism of Pue in MIRI. Pre-treatment with Pue could inhibit oxidative stress, lipid oxidation, apoptosis, and autophagy while ameliorating mitochondrial function to protect cardiomyocytes from A/R injury by adjusting HES1.

Potential mechanism of Pue in MIRI. Pre-treatment with Pue could inhibit oxidative stress, lipid oxidation, apoptosis, and autophagy while ameliorating mitochondrial function to protect cardiomyocytes from A/R injury by adjusting HES1.