Table 2 Differences in DNA methylation levels of the six CpG sites within the GAL-8 locus in Mouse artery.

From: Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis

Item

C57

AS

DC05

UO126

F

P value

 

(n = 8)

(n = 8)

(n = 8)

(n = 8)

  

CpG1(%)

57.12 ± 1.43

58.14 ± 0.73

48.24 ± 1.31*#

62.38 ± 0.44*

93.729

0.000

CpG2(%)

55.94 ± 1.80

59.74 ± 58.57

47.16 ± 2.34*#

58.20 ± 2.61*

21.396

0.001

CpG3(%)

57.76 ± 0.96

58.57 ± 1.14

48.19 ± 1.52*#

60.46 ± 1.37*

56.543

0.000

CpG4(%)

73.64 ± 1.48

75.89 ± 1.59

62.95 ± 1.73*#

75.53 ± 1.32

47.30

0.000

CpG5(%)

46.52 ± 2.49

47.85 ± 0.480

35.92 ± 0.49*#

48.25 ± 1.85

40.79

0.000

CpG6(%)

42.74 ± 1.96

42.45 ± 1.35

32.55 ± 2.22*#

42.43 ± 3.17

14.86

0.001

  1. *: P < 0.05vs C57/AS #: P < 0.05vs AS/UO126. Each group n = 8.