Table 3 Factors associated with successful TB treatment outcomes among HIV/TB co-infected patients in East and North Eastern Uganda.
Variable | Treatment outcome, n (%) | cRR (95% CI) | p-value | aRR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
Unsuccessful n = 91 | Successful n = 233 | |||||
Distance to the health facility | ||||||
≤ 5 km | 46(50.5) | 160(69.6) | 1 | 1 | ||
> 5 km | 45(49.5) | 70(30.4) | 0.44(0.27–0.74) | 0.002 | 0.88(0.65–1.18) | 0.405 |
Baseline weight | ||||||
<49.6 | 53(60.2) | 112(49.3) | 1 | 1 | ||
≥ 49.6 | 35(39.8) | 115(50.7) | 1.55(0.94–2.56) | 0.084 | 1.04(0.79–1.36) | 0.799 |
TB classification | ||||||
Extra pulmonary TB | 7(7.7) | 7(3.0) | 1 | 1 | ||
Pulmonary bacteriologically confirmed (PBC) TB | 62(68.1) | 160(68.7) | 2.58(0.87, 7.66) | 0.088 | 0.80(0.36–1.77) | 0.581 |
Pulmonary clinically diagnosed (PCD) TB | 22(24.2) | 66(28.3) | 3.00(0.94, 9.51) | 0.062 | 1.00(0.45–2.23) | 0.996 |
Treatment history | ||||||
New case | 85(93.4) | 205(88.4) | 1 | |||
Retreatment case | 5(5.5) | 26(11.2) | 2.16(0.80, 5.80) | 0.128 | 1.08(0.698–1.67) | 0.727 |
Treatment history unknown | 1(1.1) | 1(0.4) | 0.41(0.03, 6.71) | 0.535 | 1.06(0.145–7.76) | 0.954 |
WHO HIV clinical stage at baseline | ||||||
Stage 1 | 19(57.6) | 37(27.2) | 0.72(0.39–1.32) | 0.286 | 0.99(0.67–1.48) | 0.976 |
Stage 2 | 1(3.0) | 6(4.4) | 2.38(0.28, 20.04) | 0.425 | 1.11(0.48–2.56) | 0.808 |
Stage 3 | 7(21.2) | 85(62.5) | 6.89(3.05, 15.58) | < 0.001 | 1.02(0.73–1.43) | 0.896 |
Stage 4 | 6(18.2) | 8(5.9) | 0.50(0.17, 1.49) | 0.216 | 0.73(0.33–1.58) | 0.420 |
ART enrollment status | ||||||
No | 15(16.5) | 24(10.3) | ||||
Yes | 76(83.5) | 208(89.7) | 1.71(0.85, 3.43) | 0.131 | 1.22(0.78–1.93) | 0.400 |
Follow up at 5 months for sputum monitoring | ||||||
Yes | 5 (5.5) | 157 (67.4) | ||||
No | 86 (94.5) | 76 (32.6) | 0.48(0.37–0.64) | < 0.001 | 0.48(0.34–0.66) | < 0.001 |