Table 2 Mean values with standard deviation and P-values in U-tests between individual cohorts for hemodynamic, structural mechanical and morphological parameters.

From: Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms

Variable

Mean Values ± Standard Deviation

P-value

Ruptured

Unruptured (Treated)

Stable

Ruptured vs. Unruptured (treated)

Ruptured vs. Stable

Unruptured

(Treated) vs. Stable

Hemodynamic

WSSav [Pa]

0.14 ± 0.13

0.16 ± 0.14

0.24 ± 0.13

0.7134

0.0546

0.1610

WSS90 [Pa]

3.86 ± 3.73

2.56 ± 1.92

1.49 ± 0.67

0.0789

0.0347

0.0721

WSSmax [Pa]

6.65 ± 6.3

4.13 ± 3.32

3.12 ± 1.87

0.0557

0.0176

0.046

OSIav [-]

0.10 ± 0.08

0.08 ± 0.07

0.06 ± 0.043

0.6532

0.0812

0.3495

OSI90 [-]

0.289 ± 0.112

0.285 ± 0.10

0.219 ± 0.081

0.5891

0.0189

0.0102

OSImax [-]

0.373 ± 0.113

0.37 ± 0.11

0.29 ± 0.10

0.5305

0.0055

0.0032

Vav [1/s]

10.1 ± 9.8

5.6 ± 4.7

4.4 ± 3.9

0.7641

0.5152

0.4131

Vmax [1/s]

4954 ± 3215

3787 ± 2628

2985 ± 1477

0.0309

0.0096

0.0113

RRTmax [s]

16,570 ± 9299

10,317 ± 4957

7387 ± 2125

0.0256

0.0113

0.0319

HOSIA [-]

0.12 ± 0.07

0.08 ± 0.06

0.03 ± 0.02

0.4985

0.0447

0.0124

Structural Mechanical

Dav [m]

1.64E-4 ± 1.4E-4

1.62E-4 ± 1.3E-4

1.02E-4 ± 0.9E-4

0.8234

0.2693

0.2324

D90 [-]

3.80E-4 ± 2.6E-4

3.77E-4 ± 2.24E-4

2.11E-4 ± 1.66E-4

0.1897

0.0514

0.0689

Dmax [m]

5.39E-4 ± 4.6E-4

5.37E-4 ± 3.62E-4

3.35E-4 ± 2.24E-4

0.1324

0.0493

0.0531

ESav [-]

0.033 ± 0.012

0.029 ± 0.014

0.024 ± 0.010

0.1256

0.0382

0.06436

ES90 [-]

0.074 ± 0.022

0.070 ± 0.019

0.063 ± 0.017

0.0732

0.0126

0.0345

ESmax [-]

0.11 ± 0.041

0.10 ± 0.05

0.08 ± 0.039

0.0644

0.0082

0.0161

MISESav [Pa]

8.30E4 ± 3.1E4

7.32E4 ± 3.7E4

6.04E4 ± 2.3E4

0.2136

0.0042

0.0237

MISES90 [Pa]

1.76E5 ± 8.4E4

1.52E5 ± 7.2E4

1.34E5 ± 6.4E4

0.0452

1.78E-4

0.0012

MISESmax [Pa]

2.76E5 ± 1.03E5

2.44E5 ± 1.23E5

2.02E5 ± 0.98E5

0.0238

2.38E-05

1.43E-04

HESA [-]

0.28 ± 0.17

0.21 ± 0.16

0.13 ± 0.06

0.1670

0.0357

0.0657

Morphological

S [mm]

7.85 ± 3.71

6.84 ± 2.82

5.18 ± 1.38

0.3025

1.07E-4

0.0227

AR [-]

1.27 ± 0.59

1.06 ± 0.5

0.63 ± 0.34

0.1207

8.68E-06

2.99E-05

SR [-]

4.53 ± 2.37

3.49 ± 1.35

2.52 ± 0.62

0.0870

0.0003

0.0029

NSI [-]

0.16 ± 0.07

0.13 ± 0.07

0.07 ± 0.06

0.0372

5.27E-05

0.0002

EI [-]

0.14 ± 0.06

0.11 ± 0.06

0.07 ± 0.05

0.06749

8.07E-05

0.0010

UI [-]

0.08 ± 0.05

0.05 ± 0.03

0.03 ± 0.01

0.0825

0.0002

0.0055

GLN []

2.59 ± 1.26

1.83 ± 1.52

0.85 ± 0.32

0.0004

3.78E-06

3.065E-06

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