Table 2 Image features of CADASIL patients according to the occurrence of acute ischemic stroke.

From: Genetic and imaging features of CADASIL patients with acute ischemic stroke

 

AIS (+) (n = 70)

AIS (-) (n = 71)

p-value

Presence of lacune

63 (91.3)

41 (57.7)

< 0.001

Number of lacune

5.2 ± 4.8

2.9 ± 4.1

0.003

Presence of CMB

37(62.7)

32(53.3)

0.300

Number of CMB

7.4 ± 13.0

4.7 ± 8.8

0.190

White matter hyperintensities

Deep (Fazekas grade)

  

0.007

0–1

3 (4.3)

14 (19.7)

 

2

26 (37.7)

30 (42.3)

 

3

40 (58.0)

27 (38.0)

 

Perivascular (Fazekas grade)

  

0.392

0–1

3 (4.3)

7 (9.9)

 

2

13 (18.8)

15 (21.7)

 

3

53 (76.8)

49 (69.0)

 

Perivascular space (grade)

  

0.296

0

11 (15.9)

12 (16.9)

 

1

40 (58.0)

48 (67.6)

 

2–4

18 (26.1)

11 (15.5)

 

Anterior temporal pole lesions

32 (46.4)

43 (60.6)

0.092

External capsule lesions

61 (88.4)

59 (83.1)

0.370

  1. Results are presented as mean ± standard deviation or number (%).
  2. CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts stroke, AIS: acute ischemic stroke, MRI: magnetic resonance imaging, CMB: cerebral microbleeds, WMH: white matter hyperintensities,.