Table 1 Features and challenges of cancer patient’s response prediction system using radiotherapy and risk.

From: An efficient patient’s response predicting system using multi-scale dilated ensemble network framework with optimization strategy

Author [citation]

Methodology

Features

Challenges

Hu et al.18

XGBoost

It enhances predictions for individual patient risk

It effectively improves the personalized treatment regimens and individual outcomes

It provides instability outcomes

It suffers from overfitting issue

Kim et al.21

SLR

It gives high accuracy, specificity and sensitivity values

It effectively identifies the robust gene signatures of clinical relevance

It does not support early diagnosis treatment

It does not identify the younger patient’s symptoms

Bernchou et al.19

RM

It effectively identifies patients with low risk of symptomatic toxic

It reduces the multi collinearity in the genome to effectively identify the affected genome

It suffers from minimal radiation issue

It slightly decreases the survival rates

Kim et al.23

LR

It is useful for enhancing the treatment efficacy and it helps to avoid the ineffective drugs

It increases the risk prediction score

It takes a lot of time to train the model

It struggles to predict the time complexity

Chen et al.24

GSEA

It improves the prediction of prognosis and assists treatment stratification

It effectively improves the treatment of cancer patients who have mild symptoms

It is not helpful for predicting the response of patients automatically

It has a greater number of error rates

Wilkins et al.25

BCR

It effectively gives the warning of individual mortality risk

It provides dose reductions to organs at risk

Training the model requires lot of power

The implementation cost is high

Cozzarini et al.22

CNN

It maximizes the precision of delivery of the radiation dose

It gives accurate prediction response for diseased patients

It struggles to train the model with a large dataset

It is hard to predict the matched patient’s response

Defraene et al.20

ANN

It gives high dimensional dose distribution information in early stage

It gives reliable and flexible outcomes

It increases the throughput and predictive power

It is unstable and more complicated

Pati et al.26

DL

It enhances accuracy, ensuring reliable cancer diagnosis

It is capable of diagnosing breast cancer in real-time

It may require significant resources for feature reduction and transfer learning

Real-world deployment and adoption may face challenges

Sahoo et al.27

ML

It combines multiple ML models using various voting techniques for improved predictions

It provides treatment planning by enhancing relapses and metastasis prediction accuracy

The employment of multiple models increases computational overhead and complexity