Fig. 10

BOILED-Egg image of chlorogenic acid. The yellow region shows a high probability of blood brain barrier penetration, the white region shows high permeability of passive absorption by the gastrointestinal tract and the red dot shows the molecule is P-gp – means it’s not the substrate of P-gp. As shown in (A), the molecule is in the white region shows that gastrointestinal (GI) absorption and (B) shows that it cannot cross the GI track.