Fig. 4
From: Allicin induced AMPK signaling attenuated Smad3 pathway mediated lung fibrosis
Effect of allicin on a mouse model of BLM-induced lung injury. Allicin was administered from days 3 to 7 after intratracheal injection of BLM (a). Changes in body weight after BLM treatment. Body weight was defined as 1.0 on day 0 (after BLM treatment) (b). Hematoxylin and eosin staining of specimens from mice lungs on day 8 at 40× and 200× magnification. Scale bars represent 500 μm and 100 μm, respectively (c). Wright–Giemsa staining of inflammatory cells in the bronchoalveolar lavage fluid of the mice on day 8. Scale bar = 100 μm (d). Concentrations of inflammatory cells (total cells, macrophages, lymphocytes, neutrophils) in the lavage fluid of the mice in each group. Cells were counted using a manual hemocytometer (e). Data were assessed using one-way analysis of variance and are presented as mean ± SEM. *P < 0.05.
