Table 1 Patient background and univariate analysis of pathological escalation.

From: The role of PAX1 and JAM3 methylation in predicting the pathological upgrading of cervical intraepithelial neoplasia before conization

 

Upgrade group(n = 18)

Not-upgrade group(n = 70)

95%CI

P

Age

39.00 ± 11.09

42.28 ± 11.97

 

0.295

Height

161.28 ± 4.06

160.10 ± 2.91

 

0.261

Weight

58.59 ± 8.37

57.11 ± 6.51

 

0.419

BMI

36.29 ± 4.79

35.66 ± 3.88

 

0.563

Pathological diagnosis

 Benign

0

6

  

 CIN1

1

10

  

 CIN2

0

28

  

 CIN3

10

22

  

 Cervical cancer

1

2

  

 AIS

6

2

  

Conization method

 CKC

9

22

 

0.171

 Leep

9

48

  

Menopause

 Yes

2

17

 

0.339

 No

16

53

  

Number of vaginal delivery

 0

4

13

 

0.353

 1

11

35

  

 2

2

17

  

 3

1

5

  

Postcosexual bleeding

 Yes

4

8

 

0.256

 No

14

62

  

Mycoplasma infection

 Yes

8

42

 

0.290

 No

10

28

  

Type of transformation zone

   

0.768

 1

2

8

  

 2

3

15

  

 3

13

47

  

Adequate colposcopy

 Yes

14

59

 

0.498

 No

4

11

  

Interval between biopsy and conization

31.89 ± 26.74

35.01 ± 29.65

 

0.685

 ∆CtPAX1

3.51 ± 2.32

9.26 ± 6.64

3.834–7.670

< 0.001

 ∆CtJAM3

5.75 ± 2.38

10.70 ± 5.96

3.134–6.760

< 0.001

The result of the PAX1/JAM3

 Positive

17

44

 

0.009

 Negative

1

26

  

Lesion/biopsy ratio

0.588 ± 0.30

0.47 ± 0.29

 

0.146

ECC

   

0.009

 Positive

8

10

  

 Negative

10

60

  

HPV genotype

 16/18

8

30

 

0.911

 None16/18

9

36

  

 HPV negative

1

4

  
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