Table 2 Effect of trigger thumb on the development analyzed by Korea development screening test.

From: Association of trigger thumb with congenital malformations and developmental milestones among children in a nationwide birth cohort

Problem domain

Cohort (%)*

Odd ratio

Matched unexposed cohort

Trigger thumb cohort

Adjusted OR†

95% CI‡

p-value

Any six domains

9.80

10.29

1.05

0.99 to 1.16

0.0560

Gross motor skills

3.49

3.65

1.00

0.93 to 1.07

0.9159

Fine motor skills

3.66

3.85

1.02

0.95 to 1.09

0.6398

Cognition

4.70

4.66

0.97

0.92 to 1.04

0.4334

Language

4.69

4.87

1.01

0.95 to 1.07

0.8831

Social skills

3.23

2.90

0.91

0.85 to 0.98

0.0277

Self-help

2.60

2.52

0.96

0.88 to 1.04

0.3300

  1. The Korea development screening test (K-DST) evaluates six developmental domains: gross motor skills, fine motor skills, cognition, language, social skills, and self-help. Each domain has eight questions scored from 0 to 3, resulting in a total score ranging from 0 to 24 for each domain. The developmental assessments of children with trigger thumb, analyzed using generalized estimating equations (GEE) from ages 4 to 6, revealed no significant interaction with the time variable (all p values < 0.05).
  2. *Percentage of each group (matched unexposed cohorts: 101,670, trigger thumb cohorts: 10,167 patients) defined as scores indicating either a “need for follow-up” or a “recommendation for further evaluation”, †Odds ratio, ‡Confidence interval.
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