Fig. 1.

Midazolam can inhibit cell proliferation and clone. We treated A549 and H1650 cells with different concentrations of midazolam and cisplatin (The concentration of midazolam used was 20 µg/mL). (A) MTT assay showed that midazolam significantly inhibited cell proliferation of A549 and H1650 cells. (B) Colony formation assays indicated that midazolam significantly inhibited cell clone of A549 and H1650 cells. And the combination of midazolam and cisplatin has a significant synergistic effect. n=3, *P<0.05.