Fig. 2. | Scientific Reports

Fig. 2.

From: Unraveling the anti-tumor effects of midazolam in non-small cell lung cancer through the lncRNA XLOC_010706/miR-520d-5p/STAT3/autophagy pathway

Fig. 2.

Midazolam can inhibit DNA replication activity and cell invasion. We treated A549 and H1650 cells with 20 µg/mL of midazolam and/or 2 µg/mL of cisplatin for 48 hours. (A) EdU+ Staining assay showed that midazolam significantly inhibited DNA replication activity of A549 and H1650 cells. (B) Matrigel invasion assay significantly indicated that midazolam inhibited cell invasion of A549 and H1650 cells. And the combination of midazolam and cisplatin has a significant synergistic effect. n=3, *P<0.05, **P<0.01.

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