Fig. 1 | Scientific Reports

Fig. 1

From: Thioredoxin-1 inhibits NLRP3-mediated pyroptosis by regulating TXNIP in models of Alzheimer’s disease

Fig. 1

Trx-1 expression was decreased in AD models. (A) Trx-1 expression in HT22 cells treated with Aβ25−35 (40 µM) for 48 h. (B) Trx-1 expression in SH-SY5Y cells treated with Aβ25−35 (40 µM) for 48 h. (C) Trx-1 expression in PC12 cells treated with Aβ25−35 (40 µM) for 48 h. (D) The expression of Trx-1 in the hippocampus of APP/PS1 mice. Statistical analysis was performed by t-test and the statistical results were represented as means ± SD, *P < 0.05.

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