Fig. 8

Trx-1 overexpression weakened the interaction between NLRP3 and TXNIP. WT HT22 and Trx-1 overexpressing HT22 cells treated by Aβ25−35 (40 µM). (A) Primary Trx-1 antibody was employed to perform the co-IP analysis. (B) Primary TXNIP antibody was employed to perform the co-IP analysis. IgG was used as a negative control.