Fig. 1

Expression of target genes in response to IFN-γ. The expression level of immunomodulatory genes, IDO1, IDO2, IL-10, LIF, IL-6, TGF-β, COX1, COX2, TLR4, and VCAM-1 in AF-MSCs derived from samples of non-RPL and RPL groups under five different treatments; control (non-preconditioned by IFN-γ), preconditioned with two different concentrations of IFN-γ (20 IU/ml and 100 IU/ml) after two time-intervals (24 h and 72 h). The averages of five clones were analyzed using the Mann-Whitney test as dual comparisons. The p-values of non-significant differences (close to the significant level, i.e., < 0.1) are written above the compared column bars. The significant levels are marked as p-values < 0.05 (*) and < 0.01 (**).