Fig. 10

Somatic mutation analysis: Analysis of the top 20 genes with the highest mutation rates in the KIRC high- and low-risk groups (A, B); Violin plots of TMB differences between the high- and low-risk groups (C); prognostic impact of gene mutations (D); K‒M curves for risk-combined mutations, with the worst prognosis in the high-mutation population of high-risk patients (E).