Table 3 Intercellular communication relationships.
Source | Target | Ligand | Receptor | Pathway name | Probability | P value |
|---|---|---|---|---|---|---|
Tumor_cells | Macrophage | MIF | CD74_CXCR4 | MIF | 0.228 | 0 |
Tumor_cells | Macrophage | MIF | CD74_CD44 | MIF | 0.183 | 0 |
Tumor_cells | T-cell | MIF | CD74_CXCR4 | MIF | 0.178 | 0 |
Macrophage | Endothelial_cells | NAMPT | INSR | VISFATIN | 0.152 | 0 |
Tumor_cells | Endothelial_cells | SPP1 | ITGA5_ITGB1 | SPP1 | 0.135 | 0 |
vSMC | Macrophage | MIF | CD74_CXCR4 | MIF | 0.126 | 0 |
Tumor_cells | Plasma | MIF | CD74_CXCR4 | MIF | 0.125 | 0 |
vSMC | Endothelial_cells | PGF | FLT1 | VEGF | 0.118 | 0 |
Endothelial_cells | Macrophage | MIF | CD74_CXCR4 | MIF | 0.113 | 0 |
Plasma | Macrophage | MIF | CD74_CXCR4 | MIF | 0.111 | 0 |
Tumor_cells | Plasma | MIF | CD74_CD44 | MIF | 0.109 | 0 |
vSMC | Pericyte | PGF | FLT1 | VEGF | 0.107 | 0 |
Macrophage | Endothelial_cells | NAMPT | ITGA5_ITGB1 | VISFATIN | 0.104 | 0 |
vSMC | Macrophage | MIF | CD74_CD44 | MIF | 0.099 | 0 |
T-cell | Macrophage | MIF | CD74_CXCR4 | MIF | 0.097 | 0 |
