Table 4 Review of PD-L1 expression analysis before and after NAC for OHGSC.

From: Histone deacetylase 6 and programmed death ligand-1 expressions after neoadjuvant chemotherapy are upregulated in patients with ovarian high-grade serous carcinoma

Authors (year)

Cases

Histology

Regimen of NAC

PD-L1 expression after NAC

Association of prognosis

References

The present study

57

OHGSC

Platinum-based NAC

Upregulation

Association with poor PFS and OS in the group that underwent complete surgical resection

NA

Lee et al. (2022)

147

OHGSC

Platinum-based NAC

Upregulation

No association with PFS and OS

17

Kim et al. (2018)

113

OHGSC

Taxaneplatinum combination

Upregulation

No association with PFS and OS

18

Mesnage et al. (2017)

51

OHGSC

TC

Upregulation

No association with PFS and OS

16

Lo et al. (2017)

26

OHGSC

TC

No change

Not available

19

Böhm et al. (2016)

26

OHGSC

Platinum-based NAC

Upregulation

Not available

20

  1. NAC neoadjuvant chemotherapy, PD-L1 programmed death ligand-1, NA not available, OHGSC ovarian high-grade serous carcinoma, TC paclitaxel + carboplatin, PFS progression-free survival, OS overall survival.