Fig. 4 | Scientific Reports

Fig. 4

From: Glutathione-associated redox regulation alleviates radio-resistance of canine cancer stem-like cells with low proteasome activity

Fig. 4

Effect of sulfasalazine on the radio-resistance of ZsG+ cells. (A) Radiation survival curves showing radiosensitizing effects of 1,000 µM sulfasalazine. (B) Change in DSB levels due to X-irradiation after incubation with 1,000 µM sulfasalazine in ZsG− and ZsG+ cells. (C) Comparison of X-irradiation–induced DSB levels between ZsG− and ZsG+ cells after incubation with 1,000 µM sulfasalazine. Error bars correspond to the standard deviation of the mean from three independent experiments. Tukey’s multiple comparison test was used for statistical analysis. *p < 0.05, **p < 0.01, and ***p < 0.001. DSB, DNA double-strand break.

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