Fig. 4 | Scientific Reports

Fig. 4

From: Trans-ethnic Mendelian randomization analysis of membranous nephropathy and peripheral artery disease with mediating effects of thrombomodulin

Fig. 4

Selection process for significant mediators in the causal relationship of MN with PAD. MN, Membranous nephropathy; PAD, Peripheral artery diseaseMMP12, Matrix metalloproteinase-12; TM, Thrombomodulin; TF, Tissue factor; MCSF1, Macrophage colony-stimulating factor 1; IL-1β, Interleukin-1 beta; CRP, C-reactive protein; CD4, T-cell surface glycoprotein CD4; BNGF, Beta-nerve growth factor; HGF, Hepatocyte growth factor; SCF, Stem cell factor. The full MR estimates are shown in Table S6 and Table 2.

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