Table 1 Characteristics of the patients at baseline.

From: Safety and efficacy of low-temperature RA-flush solution in patients with moderate-to-severe calcified lesions (LOTA-II): a randomized, double-blind, multicenter study

 

Room-temperature group (N = 66)

Low-temperature group (N = 66)

P-value

SMD

Demographics

 Age (years)

70.86 ± 8.63

70.88 ± 7.43

0.991

0.002

 Male sex, n (%)

45 (68.2)

45 (68.2)

1.000

< 0.001

Physical measurements

 Height (cm)

165.52 ± 7.53

165.82 ± 7.56

0.818

0.040

 Weight (kg)

65.36 ± 10.91

67.83 ± 11.40

0.206

0.221

 BMI (kg/m2)

23.79 ± 3.14

24.62 ± 3.49

0.153

0.250

Risk factors

 Dyslipidemia, n (%)

17 (25.8)

17 (25.8)

1.000

< 0.001

 Hypertension, n (%)

51 (77.3)

53 (80.3)

0.670

0.074

 Current smoking, n (%)

13 (19.7)

18 (27.3)

0.305

0.179

 Diabetes, n (%)

27 (40.9)

32 (48.5)

0.381

0.153

Medical history

 Previous PCI

17 (25.8)

18 (27.3)

0.844

0.034

 Previous stroke

11 (16.7)

9 (13.6)

0.627

0.085

 Chronic renal dysfunction

5 (7.6)

9 (13.6)

0.258

0.198

 Peripheral artery disease

4 (6.1)

4 (6.1)

1.000

< 0.001

Left ventricular ejection fraction (%)

52.93 ± 7.66

54.31 ± 7.59

0.309

0.181

Presentation at admission

  

0.822

0.109

 Silent ischemia, n (%)

41 (62.1)

38 (57.6)

  

 Stable angina, n (%)

18 (27.3)

19 (28.8)

  

 Unstable angina, n (%)

7 (10.6)

9 (13.6)

  

Medication before PCI

 Aspirin, n (%)

66 (100.0)

66 (100.0)

1.000

< 0.001

 P2Y12 inhibitor, n (%)

66 (100.0)

66 (100.0)

1.000

< 0.001

 Clopidogrel, n (%)

36 (54.5)

32 (48.5)

0.486

0.121

 Ticagrelor, n (%)

30 (45.5)

34 (51.5)

0.486

0.121

 Oral anticoagulant, n (%)

11 (16.7)

10 (15.2)

0.812

0.057

 Statin, n (%)

66(100.0)

66(100.0)

1.000

< 0.001

 Beta-blocker, n (%)

22 (33.3)

31 (47.0)

0.110

0.281

 ACEI or ARB, n (%)

46 (69.7)

50 (75.8)

0.434

0.611

  1. Values are expressed as the median (interquartile range) for continuous variables with abnormal distribution and described as the mean ± standard deviation with normal distribution, or frequency (percentage) for categorical variables in the table. ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, BMI body mass index, PCI percutaneous coronary intervention, SMD standardized mean difference.