Table 2 Target lesion characteristics and interventional properties.

From: Safety and efficacy of low-temperature RA-flush solution in patients with moderate-to-severe calcified lesions (LOTA-II): a randomized, double-blind, multicenter study

 

Room-temperature group (N = 66)

Low-temperature group (N = 66)

P-value

SMD

Target lesion location

  

0.85

0.131

 Left anterior descending, n (%)

56 (84.9%)

55 (83.3%)

  

 Right coronary artery, n (%)

8 (12.1%)

10 (15.2%)

  

 Left circumflex, n (%)

2 (3.0%)

1 (1.5%)

  

QCA for target lesion

 Lesion length (mm)

52.86 ± 14.48

51.00 ± 16.79

0.50

0.119

 Reference diameter (mm)

3.23 ± 0.40

3.24 ± 0.30

0.81

0.041

 Diameter stenosis (%)

79.32 ± 8.00

77.73 ± 9.02

0.29

0.187

RA-related procedure properties

 Planed RA strategy (%)

53 (80.3%)

53 (80.3%)

1.000

< 0.001

 Final burr size (mm)

1.65 ± 0.18

1.66 ± 0.18

0.633

0.083

 Final burr-to-vessel

0.51 ± 0.05

0.51 ± 0.05

0.977

0.009

 Initial RA burr speed (rpm)

160196.97 + 1026.12

161181.82 + 1983.85

< 0.001

0.624

 Total RA time (s)

66.26 ± 14.21

70.08 ± 15.90

0.148

0.253

 Maximal RA speed deceleration (rpm)

8000 (8000, 9000)

8000 (7250, 9000)

0.353

0.227

 RA speed decelerations exceeding 5000 rpm (%)

66 (100.0%)

66 (100.0%)

1.000

< 0.001

 Initial solution temperature (°C)

22.63 ± 1.29

2.08 ± 1.02

< 0.001

17.664

 Final solution temperature (°C)

22.86 ± 1.32

6.06 ± 1.91

< 0.001

10.230

Intervention properties post RA

 Balloon pre-dilatation (%)

66 (100.0%)

66 (100.0%)

1.000

< 0.001

 Only non-compliant balloon used (%)

25 (37.9%)

31 (47.0%)

0.291

0.185

 Modified balloon used (%)

18 (27.3%)

15 (22.7%)

0.546

0.105

 Maximal pre-dilatation balloon diameter (mm)

2.79 ± 0.39

2.74 ± 0.39

0.440

0.135

 Maximal pre-dilatation balloon pressure (atm)

15.06 ± 4.11

16.61 ± 4.41

0.039

0.363

 No. of stents per lesion

2.18 ± 0.63

2.24 ± 0.72

0.609

0.089

 Total stent length per lesion (mm)

62.53 ± 15.44

62.55 ± 18.86

0.996

0.001

 Average stent diameter (mm)

3.05 ± 0.38

3.06 ± 0.32

0.941

0.013

 Balloon post-dilatation (%)

66(100.0%)

66(100.0%)

1.000

< 0.001

 Maximal post-dilatation balloon diameter (mm)

3.46 ± 0.52

3.45 ± 0.51

0.899

0.022

 Maximal post-dilatation balloon pressure (atm)

18.61 ± 3.86

19.33 ± 3.07

0.233

0.209

  1. Values are expressed as the median (interquartile range) for continuous variables with abnormal distribution and described as the mean ± standard deviation with normal distribution, or frequency (percentage) for categorical variables in the table. QCA quantitative coronary analysis, RA rotational atherectomy, SMD standardized mean difference.
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