Fig. 6 | Scientific Reports

Fig. 6

From: Delivery of bone marrow mesenchymal stem cell-derived exosomes into fibroblasts attenuates intestinal fibrosis by weakening its transdifferentiation via the CCN2-TGF-β axis

Fig. 6

BMSC-Exo inhibits CCD-18Co activation via CCN2 in vitro as evidenced by Western blotting analysis. (A,B) CCD-18Co representative immunoblot bands for the CCN2 (A) and TGF-β (B) proteins in fibroblasts between ov-NC and ov-CCN2 groups. (C) Western blot analysis of the Collagen I, N-cadherin, and α-SMA after CCN2 overexpression and stimulation of fibroblasts with TGF-β and BMSC-Exo. n = 3; *P < 0.05, **P < 0.01.

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