Fig. 7 | Scientific Reports

Fig. 7

From: Delivery of bone marrow mesenchymal stem cell-derived exosomes into fibroblasts attenuates intestinal fibrosis by weakening its transdifferentiation via the CCN2-TGF-β axis

Fig. 7

CCN2 plays a significant role in the anti-fibrosis process in vivo. (A) Detection of CCN2 and TGF-β expression by immunohistochemistry staining in the three different groups of mice. (B) Representative bands showing the expression of CCN2 and α-SMA in colonic sections. (C) Western blot and quantification results of Collagen I, N-cadherin, and α-SMA and Arg1 in mice. n = 4; *P < 0.05, **P < 0.01, ***P < 0.001.

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