Fig. 7
From: rhaFGF promotes acute diabetic wound healing by suppressing chronicity of inflammation
The effects of rhaFGF on the protein levels of NLRP3, ASC, Caspase-1, IL-1β, and IL-18 in wound tissue in control and diabetic mice. (A) Representative immunoblots showed the protein levels of NLRP3, ASC, Caspase-1, IL-1β, and IL-18 in all groups. Band intensities were quantitated for NLRP3 (B), ASC (C), Caspase-1 (D), IL-1β (E), and IL-18 (F) protein after normalization to β-actin. Diabetic mice (DM) exhibited significantly increased expression of all measured proteins compared to controls and rhaFGF treatment (DM + rhaFGF) significantly reduced this increase, while there was no significant difference between Con and Con + rhaFGF groups. *p < 0.05 and ***p < 0.001.
