Table 1 The different CC50, IC50, and SI values in embryonated chicken SPF eggs and their embryonic toxicity against NDV.

From: Antiviral activity of newly synthesized pyrazole derivatives against Newcastle disease virus

Compds.

aCC50

bIC50

cSI (%)

2

> 800

≤ 10

80

3

> 700

≤ 8

87.5

4

> 400

≤ 5

80

6

> 200

≤ 2

100

7

> 500

≤ 5.5

90.9

9

> 300

≤ 3

100

10

> 800

≤ 9

88

11

> 500

≤ 6

83

Amantadine

> 300

≤ 3

100

  1. NDV newcastle disease virus.
  2. aCC50: Cytotoxicity concentration fifty.
  3. bIC50: Inhibitory concentration fifty c SI: Selectivity index.