Table 2 Multivariate Cox proportional hazard model of breast cancer-specific survival (BCSS) and overall survival (OS) in all patients.

Age

70–74

Reference

Reference

75–79

1.226(1.046–1.436)

0.012

1.494(1.369–1.629)

< 0.001

Race

White

Reference

Reference

Black

1.278(1.015–1.609)

0.037

1.223(1.063–1.407)

0.005

Other^a

0.457(0.306–0.683)

< 0.001

0.580(0.475–0.707)

< 0.001

Marital status

Married

Reference

Reference

Not married^b

1.170(1.001–1.367)

0.048

1.285(1.177–1.402)

< 0.001

Grade

I

Reference

Reference

II

2.054(1.502–2.810)

< 0.001

1.245(1.102–1.407)

< 0.001

III&IV

3.330(2.395–4.629)

< 0.001

1.610(1.395–1.857)

< 0.001

Tumor status

T1b

Reference

Reference

0.01

T1c

1.668(1.239–2.245)

< 0.001

1.466(1.318–1.631)

< 0.001

T2

2.835(2.093–3.841)

< 0.001

2.023(1.578–2.592)

< 0.001

Nodal status

N0

Reference

Reference

N1

1.668(1.381–2.013)

0.222

1.221(0.955–1.562)

0.087

N2

3.749(2.925–4.805)

< 0.001

2.576(2.103–3.155%

< 0.001

Subtype

HR-/HER2-

Reference

Reference

HR-/HER2+

0.560(0.386–0.812)

< 0.001

0.744(0.577–0.961)

0.024

HR+/HER2-

0.548(0.432,0.695)

< 0.001

0.683(0.576–0.810)

< 0.001

HR+/HER2+

0.528(0.397–0.703)

< 0.001

0.763(0.630–0.923)

0.005

Surgery

Mastectomy

Reference

Reference

Partial mastectomy

1.106(0..916–1.335)

0.297

1.067(0.951–1.197)

0.269

Radiotherapy

No/unknown

Reference

Reference

Yes

0.648(0.541–0.775)

< 0.001

0.695(0.625–0.773)

< 0.001

Chemotherapy

No

Reference

Reference

Yes

1.219(0.983–1.511)

0.071

0.772(0.679–0.879)

< 0.001