Fig. 2 | Scientific Reports

Fig. 2

From: Ursolic and oleanolic acids suppress MNNG induced malignant transformation of human gastric mucosal epithelium by regulating the PI3 K/AKT pathway

Fig. 2

Docking modes of compound and core targets. (a) Ber-AKT1 (binding sites: GLN104 and GLN61). (b) Ber-PIK3 CA (binding sites: VAL125). (c) UA-AKT1 (binding sites: ARG25 and ASN53). (d) UA-PIK3 CA (binding sites: LYS924, GLN928, and GLU172). (e) OA-AKT1 (binding sites: ARG25 and ASN53). (f) OA-PIK3 CA (binding sites: LYS468, GLN682, and ARG683). AKT1, protein kinase 1; PIK3 CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.

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