Table 1 Study demographics and clinical behavioral measures.

From: A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization

 

HC (N = 135)

AN (total N = 114)

Group comparisons

Post-hoc comparisons

Effect sizes d

AN-R (n = 61)

AN-BP (n = 53)

HC vs. AN-R

HC vs. AN-BP

AN-R vs. AN-BP

Mean (SD)

N

Mean (SD)

N

Mean (SD)

N

Statistics (df)

P-value

Age

31.0 (11.2)

135

28.9 (11.8)

61

36.7 (10.7)

53

15.1 (2)

0.001

HC < AN-BP (P = .004) 

0.18

0.52

0.69

AN-R < AN-BP (P = .001)

Body Mass Index, kg/m2

20.8 (2.4)

135

14.3 (2.2)

61

15.3 (1.9)

53

169.0 (2)

< 0.001 

AN-R < HC (P < .001)

2.78

2.42

0.50

AN-BP < HC (P < .001)

TIV, ml

1481.4 (109.8)

135

1461.2 (114.2)

61

1444.6 (101.1)

53

2.3* (2, 246)

.100

-

0.18

0.34

0.15

Duration of illness, years

-

-

9.3 (8.8)

50

15.1 (8.6)

44

658.5

.001

-

-

-

0.67

Psychotropic medication

-

-

-

22/61

-

27/53

2.5† (1)

.110

-

-

-

0.15

JART

FSIQ

108.8 (7.3)

97

99.2(10.5)

45

103.2 (8.8)

32

30.2 (2)

< 0.001

AN-R < HC (P < .001)

1.14

0.73

0.38

AN-BP < HC (P = .007)

EDE-Q

Global

0.7 (0.7)

119

1.9 (1.4)

53

3.3 (1.6)

41

84.8 (2)

< 0.001

HC < AN-BP (P < .001)

1.24

2.58

0.94

HC < AN-R (P < .001)

AN-R < AN-BP (P = .007)

Restraint

0.6 (0.9)

119

1.7 (1.6)

53

3.2 (1.8)

41

68.2 (2)

< 0.001

HC < AN-BP (P < .001) 

0.95

2.18

0.91

HC < AN-R (P < .001)

AN-R < AN-BP (P = .001)

Eating

0.2 (0.5)

119

1.7 (1.5)

53

3.2 (2.0)

41

106.1 (2)

< 0.001

HC < AN-BP (P < .001)

1.62

2.74

0.86

HC < AN-R (P < .001)

AN-R < AN-BP (P = .039)

Weight

0.9 (1.0)

119

2.1 (1.6)

53

3.4 (1.9)

41

60.7 (2)

< 0.001

HC < AN-BP (P < .001)

0.99

1.94

0.75

HC < AN-R (P < .001)

AN-R < AN-BP (P = .010)

Shape

1.2 (1.1)

119

2.3 (1.6)

53

3.6 (1.7)

41

61.8 (2)

< 0.001

HC < AN-BP (P < .001) 

0.86

1.88

0.79

HC < AN-R (P < .001)

AN-R < AN-BP (P = .007)

STAI

State

36.3 (9.2)

117

49.5 (13.2)

49

55.0 (12.0)

35

76.9 (2)

< 0.001

HC < AN-BP (P < .001) 

1.25

1.89

0.43

HC < AN-R (P < .001)

Trait

44.2 (13.1)

116

58.9 (18.1)

49

61.7 (10.9)

35

61.0 (2)

< 0.001

HC < AN-BP (P < .001)

1.00

1.39

0.18

HC < AN-R (P < .001)

BDI-II

5.9 (5.8)

122

22.3 (12.3)

53

28.7 (13.5)

40

102.7 (2)

< 0.001

HC < AN-BP (P < .001)

1.97

2.73

0.50

HC < AN-R (P < .001)

  1. * F values, † χ2 values, Statistics without a symbol are H values, N Number of participants, SD standard deviation, df degrees of freedom, AN anorexia nervosa, HC healthy control, AN-R anorexia nervosa restricting type.
  2. AN-BP anorexia nervosa binge/purge type, JART Japanese adult reading test, EDE-Q eating disorder examination questionnaire, STAI state-trait anxiety inventory, BDI-II beck depression inventory-II.
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